遗传性非息肉病性大肠癌,Hereditary nonpolyposis colorectal cancer
1)Hereditary nonpolyposis colorectal cancer遗传性非息肉病性大肠癌
1.Clinical characteristic,diagnosis and therapy of hereditary nonpolyposis colorectal cancer in 32 cases of 11 families;遗传性非息肉病性大肠癌11个家系32例的临床特点与诊治
2.Background and ObjectivesHereditary nonpolyposis colorectal cancer (HNPCC) is an autosomal and dominantly inherited cancer predisposition caused by a constitutional defect in a mismatch repair (MMR) gene, with a disease penetrance that approaches 80-90%.研究背景与目的遗传性非息肉病性大肠癌(HNPCC)是由于DNA错配修复基因(MMR)发生胚系突变所致的一种单基因显性遗传性疾病,占所有结直肠癌的5%-15%,外显率达80%-90%,多见于青年患者(年龄≤40岁)。
英文短句/例句
1.Clinical Analysis and Molecular Genetic Study of Hereditary Nonpolyposis Colorectal Cancer Kindreds;遗传性非息肉病性大肠癌（HNPCC）家系研究
2.Clinicopathologic characteristics,diagnosis,and treatment of 30 patients with hereditary nonpolyposis colorectal cancer遗传性非息肉病性大肠癌30例临床病理特点与诊治分析
3.The analysis of clinicopathological feature and prognosis of hereditary non-polyposis colorectal cancer遗传性非息肉病性大肠癌临床病理特点和预后分析
4.Gene Diagnosis of Hereditary Nonpolyposis Colorectal Cancer and Preliminary Construction of Its Mutation Database;遗传性非息肉病性大肠癌基因诊断及其基因突变库的初步构建
5.Expressions of MMP-7、TIMP-2 and their correlation to the biological behaviours of hereditary nonpolyposis colorectal cancerMMP-7和TIMP-2表达在遗传性非息肉病性大肠癌侵袭转移中的作用
6.Analyze of Clinical Phenotype of the Hereditary Nonpolyposis Colorectal Cancer in Northerner of China and Basic Research of Its Molecular Genetics;中国北方人遗传性非息肉病性大肠癌临床表型分析及其分子遗传学基础研究
7.The Significant of Fas/FasL Protein Expression and the Quantity of TIL in Hereditary Nonpolyposis Colorectal Cancer;遗传性非息肉病性大肠癌癌组织中Fas/FasL蛋白的表达及TIL计数的意义
8.One Family Report of Fulfilling Chinese HNPCC Criteria;符合中国人遗传性非息肉病性大肠癌家系标准的一家系报告附文献综述
9.Molecular and Clinical Pathology Features of Hereditary Non-Polyposis Colorectal Cancer (HNPCC);遗传性非息肉病性结直肠癌的分子遗传及临床病理研究
10.Analysis of the Phenotype Features and Their Molecular Mechanism of Hereditary Nonpolyposis Colorectal Cance (HNPCC);遗传性非息肉病性结直肠癌表型分析及分子遗传基础研究
11.Clinical and pathological analysis of 8 hereditary nonpolyposis colorectal cancer pedigrees遗传性非息肉病性结直肠癌8个家系临床及病理分析
12.Study of Screening Hereditary Nonpolyposis Colorectal Cancer Families Based on mRNA Sequencing;基于胚系mRNA异常筛选遗传性非息肉病性结直肠癌家系的研究
13.An Study of Methylation of Mismatch Repair Gene in Hereditary Nonpolyposis Colorectal Cancer;遗传性非息肉病性结直肠癌中错配修复基因甲基化的研究
14.Detection of hMLH1/hMSH2 expression for identifying patients with hereditary non-polyposis colorectal carcinomahMLH1和hMSH2表达在中国人遗传性非息肉病性结直肠癌遴选中的价值
15.Systematic Review and Meta-analysis of Diagnostic Tests for Hereditary Nonpolyposis Colorectal Cancer遗传性非息肉病性结直肠癌诊断试验Meta分析研究
16.Characterization of Genotype-phenotype and Clinico-pathological Features in Chinese Hereditary Nonpolyposis Colorectal Cancer Families;中国人遗传性非息肉病性结直肠癌家系收集、整理及分子遗传学和临床病理特征分析
17.Clinicopathological and Molecular Genetic Study of Chinese Hereditary Nonpolyposis Colorectal Cancer (HNPCC)中国人遗传性非息肉病性结直肠癌（HNPCC）临床病理特征及分子遗传学研究
18.Mutation of Related Gene in Chinese Patients with Hereditary Colorectal Polyposis;中国人遗传性结直肠息肉病患者基因突变的检测
相关短句/例句
Hereditary non-polyposis colorectal cancer遗传性非息肉病性大肠癌
1.Hereditary non-polyposis colorectal cancer (HNPCC),also called Lynch syndrome,is an autosomal-dominantly inherited disease and is associated with germline mutations in mismatch repair(MMR)genes and microsatellite instability(MSI).遗传性非息肉病性大肠癌(HNPCC)是一种由错配修复基因(MMR)突变造成的常染色体显性遗传病,又称Lynch综合征,是遗传性大肠癌的代表。
2.Objective To investigate the relationship between microsatellite instability(MSI) and the expression of transforming growth factor β receptor II(TGFβRII),mismatch repaire(MMR) proteins in Hereditary Non-polyposis Colorectal Cancer(HNPCC).目的观察遗传性非息肉病性大肠癌(HNPCC)和大肠腺瘤癌组织中TGFβRII、错配修复基因(hMLH1、hMSH2、hMSH6)蛋白表达和微卫星不稳定(MSI)的关系。
3)hereditary non-polyposis colorectal cancer遗传性非息肉性大肠癌
4)herediary nonpolyposis colorectal cancer遗传性非息肉病性大肠癌(HNPCC)
5)hereditary nonpolyposis colorectal cancer(HNPCC)遗传性非息肉病性大肠癌/HNPCC
6)Hereditary nonpolyposis colorectal cancer遗传性非息肉病性结直肠癌
1.Hereditary nonpolyposis colorectal cancer:an analysis of 11 kindreds.;遗传性非息肉病性结直肠癌11家系临床病理分析
2.Clinical and pathological analysis of 8 hereditary nonpolyposis colorectal cancer pedigrees遗传性非息肉病性结直肠癌8个家系临床及病理分析
3.Objective To gain an insight into the large intragenic hMSH2 and hMLH1 deletions in Chinese hereditary nonpolyposis colorectal cancer(HNPCC)families.目的了解中国人遗传性非息肉病性结直肠癌(HNPCC)家系hMSH2和hMLH1基因大片段缺失特点。
延伸阅读
非妊娠性绒癌非妊娠性绒癌非妊娠性绒癌在绒癌中占极少数。系来自自身一代原始生殖细胞分化异常所致(自体细胞变成)的肿瘤，故称为非妊娠性绒癌或原发性绒癌。男、女均可发病，在女性可发生于未婚或绝经后。原发瘤可发生于男、女性的生殖系统内，也可在生殖系统外(如纵隔、腹膜后、肺、食管、胃、肝、肾、膀胱、颅内等部位)。发生于生殖系统者，常和卵巢生殖细胞瘤(无性细胞瘤、未成熟型畸胎瘤、内胚窦瘤)或睾丸精原细胞瘤同时存在。由于本病罕见，多数的肿瘤组织和临床症状复杂，确诊困难。就诊病人也多为晚期，往往疗效差。化疗可以选用EMA/CO或PVB方案，合并卵巢精原细胞瘤或卵巢无性细胞瘤者，可加用放疗。
