肿瘤抑制基因,Tumor suppressor gene
1)Tumor suppressor gene肿瘤抑制基因
1.The evidence from cancer cell lines and primary tumor tissues suggests that WWOX is a tumor suppressor gene and that its inactivation contributes to cancer devel.原发肿瘤组织及细胞系的研究证明该基因为肿瘤抑制基因,其失活可能导致肿瘤的发生,基因敲除实验证实了上述假设。
2.Objectives To locate the concentrate area of loss of heterozygosity(LOH)in children with acute lymphoblastic leukemia,and explore the new tumor suppressor gene and its clinical significance.目的定位儿童急性淋巴细胞白血病(ALL)杂合性缺失(LOH)的集中区,探讨新的肿瘤抑制基因及与临床相关性。
3.2 is a putative tumor suppressor gene.2区域的候选肿瘤抑制基因 ,在许多肿瘤 ,特别是环境致癌物引起的上皮肿瘤中经常发生改变 ,在辐射引起的癌症中也有改变 ,参与细胞周期和细胞凋亡的调控 ,但其作用的机理尚未完全阐明。
英文短句/例句
1.Functional Study of RbAp46, A Novel Tumor Suppressor Gene;RbAp46——一种新的肿瘤抑制基因
2.The Research Advancement Of The Tumor-Restraining Gene Maspin肿瘤抑制基因Maspin的研究进展
3.Epigenetic Regulation of Tumor Suppressor Gene PTEN and Its Anticancer Mechanisms肿瘤抑制基因PTEN的表观遗传调控及其抗肿瘤机制研究
4.STUDY OF SUPPRESSOR ONCOGENE PTEN/MMAC1/TEP1 PROTEIN EXPRESSION IN COLORECTAL ADENOMA AND CARCINOMA;大肠良恶性肿瘤PTEN/MMAC1/TEP1肿瘤抑制基因的表达研究
5.Research on Abnormal Methylation of Tumor Suppressors in Human Gastric Cancer;胃癌中若干肿瘤抑制基因异常甲基化的研究
6.Research Development of Aberrant Methylation of Tumor Suppressor Gene in Gastric Tumor肿瘤抑制基因异常甲基化与胃癌的研究进展
7.Tumor Suppresser Gene PTEN Was Induced by TSA and X-Ray;TSA刺激与X-ray处理促进肿瘤抑制基因PTEN的表达
8.Researching of the Relationship between the Tumor Suppressor Gene nm23-H1 and Nasopharyngeal Carcinoma;肿瘤抑制基因nm23-H1与鼻咽癌相关性研究
9.cDNA Cloning and Sequence Analysis of the Gene of Porcine Tumor Suppressor Candidate 5猪肿瘤抑制基因候选5的克隆与序列分析
10.Cloning of Tumor Suppressor Gene p53 and Study of the Relation between the p53 Gene and Lymphocystis Disease in Cultured Japanese Flounder (Paralichthys Olivaceus);养殖牙鲆肿瘤抑制基因p53的克隆及与淋巴囊肿病关系的研究
11.A Study on Metastasis Suppression Effects of KAI1/CD82 Gene;KAI1/CD82基因肿瘤转移抑制作用研究
12.Investigation of the Target Genes Involved in Tumor Cell Apoptosis Induced by HDAC InhibitorHDAC抑制剂抗肿瘤效应靶基因的研究
13.Relationship between a novel anti-oncogene TSLC1 and digestive apparatus tumor新抑癌基因肺癌肿瘤抑制物1(TSLC1)与消化系肿瘤的关系
14.Many cancers arise due to defects in genes that normally suppress tumor growth.众多癌症的发生是因抑制肿瘤生长的基因缺乏。
15.Cloning and Expression of Angiostatin;肿瘤血管生长抑制因子Angiostatin基因的克隆及表达
16.Anti-metastatic Mechanisms of Reinforcing Qi and Nourishing Yin and Gene Expression Profile Analysis益气养阴方抑制肿瘤转移及对肿瘤相关基因表达谱的影响
17.AKAP12 Promoter Hypermethylation and Inhibitory Effect on the Tumor Progression and Metastasis in Human Colorectal Carcinoma结直肠癌中AKAP12基因甲基化及其肿瘤抑制作用
18.Current Study of Basal Cell Carcinoma and Metastasis Suppressor Gene Kai1基底细胞癌与肿瘤转移抑制基因Kai1的研究现状
相关短句/例句
tumor suppressor genes肿瘤抑制基因
1.Analysis on loss of heterozygosity of fourtumor suppressor genes in hepatocellular adenoma;肝细胞腺瘤肿瘤抑制基因杂合性缺失分析
2.Chromosome 14q may harbor multipletumor suppressor genes in primary glioblastoma multiforme;原发性胶质母细胞瘤染色体14q上可能存在多个肿瘤抑制基因(英文)
3.In order to identify candidatetumor suppressor genes (TSGs) in childhood acute lymphoblasticleukemia (ALL), firstly, loss of heterozygosity (LOH) of 6q16.为了克隆儿童急性淋巴细胞性白血病(ALL)候选肿瘤抑制基因,首先选取分布于6q16。
3)tumor suppressor肿瘤抑制基因
1.These data together with the localization of p73 on chromosome 1p36, a special region, led to the hypothesis that p73 hastumor suppressor activity just like p53.p73基因过表达能够激活p53的靶基因从而诱导细胞凋亡,也能对异常的细胞增殖和一些DNA损伤事件产生反应性活化,同时因为p73在1p36的特殊定位,研究者认为p73基因或许像p53一样是一个肿瘤抑制基因。
2.Recent studies have revealed thattumor suppressor PTEN does not only closely relate to the development and differentiation of brain but also get extensively involved into the pathophysiological processes of ischemic brain injury.近年来研究表明,肿瘤抑制基因PTEN不仅与脑发育和分化调控密切相关,而且其介导的信号网络还广泛参与了缺血性脑损伤的病理生理过程。
3.Advance of the research in thetumor suppressor gene LKB1;在这篇综述中 ,我们详述一些最近令人振奋的研究成果 :LKBl作为一种肿瘤抑制基因可能是通过改变细胞的凋亡而起作用 ,在体内是通过与其它蛋白相互作用如磷酸化或甲基化而控制细胞。
4)tumor suppression gene肿瘤抑制基因
1.Objective To detect the status of loss of heterozygosity(LOH) on chromosome 13q11-12 in esophageal squamous cell carcinoma(ESCC) and determine a minimum loss region of ESCC relatedtumor suppression gene(TSG).目的分析食管鳞状细胞癌(esophageal squamous cell carcinoma,ESCC)在13号染色体长臂11-12区(13q11-12)上的等位基因杂合性丢失(LOH),以期寻找13q11-12区上可能存在的与食管鳞状细胞癌有关肿瘤抑制基因的缺失区域。
5)Tumor suppressing gene基因肿瘤抑制
6)Tumor suppressor gene p16肿瘤抑制基因p16
延伸阅读
肿瘤抑制基因分子式：CAS号：性质：是一类肿瘤抑制基因的总称。第一个分离到的抑癌基因是Rb基因(retinoblastoma gene)或称视网膜母细胞瘤基因。现已证明：结肠癌等多种癌症也检出Rb基因的缺陷。已被证实的抑癌基因有10多种，都是通过缺失或失活而致细胞恶性转化的一类基因。这类基因的作用机制涉及基因表达调控、细胞分裂、分化过程，也可能与生长因子、激酶、信息在胞内的传递密切相关。
