Though Lucy is often tired his job he is never tired it. In fact he enjoys it. A of

问题补充：

Though Lucy is often tired his job, he is never tired it. In fact , he enjoys it.

A of, with B with, with C of, from D from, of

答案：

解析：：考查固定词组。Be tired from…因…而疲惫；be tired of对…感到厌倦；句意：尽管Lucy 经常因为工作而疲惫，但是他从来没有厌倦过工作，实际上，他非常喜欢这份工作。故D正确。