Eugene s never willing to alter any of his opinions. It s no use with him.A. to argueB.

问题补充：

Eugene s never willing to alter any of his opinions. It s no use with him.

A. to argue

B. arguing

C. argued

D. having argued

答案：

A. to argue

B. arguing

C. argued

D. having argued

解析：

It is no use doing sth．做某事没有用处。A，动词不定式结构不能放在It is no use句型之后；B，符合It is no use＋v．-ing句式习惯的要求；C，过去分词不用于此句型；D，本句式为固定的句子结构，不宜采用动词的完成式结构。It is no use doing sth．是高中极为重要的一个句型，其中It为句子中的形式主语，而句子的真正主语是动名词短语。