结肠靶向,colon targeting
1)colon targeting结肠靶向
1.Preparation of Kangfuxincolon targeting micro-pellets;康复新结肠靶向微丸的制备工艺
2.In vivo/in vitro evaluation of Kangfuxincolon targeting capsules;康复新结肠靶向胶囊的体内外评价
3.Conclusions: This research provided a way for traditional Chinese drug preparation ofcolon targeting.目的 :考察中药制备结肠靶向给药的可能。
英文短句/例句
1.Study on membrane-forming effect and colon-targeting property of colon-specific microporous membrane结肠靶向微孔膜的成膜效果和结肠靶向性研究
2.Preparation and Study of Mesalazine and Metrmidazol Colon Specific Pellets;美沙拉嗪/甲哨唑结肠靶向微丸的研制
3.The Study of Indomethacin Colon Targeted and Time Controlled Tablets;吲哚美辛结肠靶向定时释放片的研究
4.Development of IN Pellets for Microbially Triggered Colon Drug Delivery酶触型结肠靶向吲哚美辛微丸的研制
5.Coating Technology of pH and Enzymes Dependent Changkangning Tablets for Colon-specific DeliverypH-酶依赖型肠康宁结肠靶向片的包衣工艺研究
6.Time-Lag Combined pH-Sensitve Drug Conlon-Specific Delivery System--The Study on Preparing Hydrochloric Levofloxacin Oral Colon-specific Delivery Pellets;时滞与pH敏感结合型结肠靶向制剂——盐酸左氧氟沙星结肠靶向小丸的研制
7.Study on Budesonide Colon-targeted Site-specific Dosage Forms;布地奈德结肠靶向定位给药制剂的研究
8.Studies on the Synthesis and in Vitro Release of Colon-specific Polymer Drugs;结肠靶向高分子药物的合成与体外释放研究
9.Study on Bacterially Triggered Colon-Specific Preperation of Hydrocortisone;氢化可的松菌群触发型结肠靶向制剂的研究
10.Development of Film-Coated Pellets of 5-Fluorouracil for Microbially Triggered Colon Drug Delivery;酶触型5-氟尿嘧啶结肠靶向包衣微丸的研制
11.Preparation and Evaluation of Budesonide Pulsatile Release Tablet for Colon-specific Delivery;布地奈德结肠靶向脉冲控释片的制备及评价
12.Preparation of Colon Targeted Rhubarb Capsule and Its Quality Evaluation;复方大黄结肠靶向胶囊的制备及质量评价
13.The Preparation of Paeonol-β-cyclodextrin Colon-targeted Tablets丹皮酚-β-环糊精包合物结肠靶向片的研制
14.Study and Application of Natural Polysaccharides for Colon-Specific Drug Carrier天然多糖在结肠靶向药物载体中的研究与应用
15.Localization study on sodium 4-amino salicylic acid colon-targeting capsule4-氨基水杨酸钠结肠靶向胶囊定位研究
16.Determination of baicalin from Kuijiekang colon targeting pellets in rat plasma溃结康结肠靶向微丸中黄芩苷在大鼠体内血药浓度测定
17.Azo Polymeric-drug as Colonic Specific Drug Delivery System: Synthesis, Biodegradation and Drug Delivery Properties;偶氮类结肠靶向高分子药物的合成、生物降解和释药性能的研究
18.The Evaluation of Carboxymethyl Chitosan Microspheres Containing Levofloxacin for Colon-specific Drug Delivery in Vitro and in Vivo;左氧氟沙星羧甲基壳聚糖凝胶、微球结肠靶向释药的应用基础研究
相关短句/例句
colon-specific结肠靶向
1.Polysaccharides are used ascolon-specific drug delivery carriers because they can be degraded by enzymes produced by colon bacteria.多糖能被结肠内的菌群降解,而被用作结肠靶向给药的载体。
2.The aim of this work was to investigate guar gum/ethylcellulose mix coated pellets for potentialcolon-specific drug delivery.体外研究瓜尔胶/乙基纤维素混合包衣小丸的结肠靶向性。
3.slected different properties chemical elements as model drugs,and in view of above problems,studied systematically by free film and membrane controlled preparation according to the requirement ofcolon-specific.针对当前膜控材料在中药结肠靶向给药系统中应用的相关性质、影响因素及其与药物匹配性认识不足的问题,本论文以pH敏感型和酶触发型材料为研究对象,以不同性质的化学组分为模型药物,根据结肠递药的要求,从游离膜和膜控制剂两种形式对上述问题进行系统研究,并分析两种形式下研究结果的相关性,揭示各膜控材料用于结肠靶向给药的相关性质及其影响因素,明确其在中药结肠靶向制剂中的适宜性,为中药膜控型结肠靶向制剂的设计、制备提供科学依据。
3)colon specific结肠靶向
1.In this article , a review of research in thecolon specific drug delivery based on azo polymers in which azo groups are located in the main chain, cross links, or in branches, is given.在人体消化道中 ,偶氮键仅能被结肠厌氧菌代谢的偶氮还原酶还原而断裂 ,偶氮聚合物可作为潜在的高定位性的结肠靶向药物缓释载体。
2.Azo polymers may be expected ascolon specific drug delivery systems because azo bonds in polymers can be reduced by azoreductase generated by colonic bacteria.偶氮聚合物中的偶氮键可被结肠菌丛产生的偶氮还原酶催化还原 ,可用作高定位性的结肠靶向给药药物载体。
4)colon-targeted结肠靶向
1.Verification ofcolon-targeted release of Changankang Pellets;肠安康微丸结肠靶向验证实验
5)colon-targeting结肠靶向性
1.OBJECTIVE To evaluate thecolon-targeting effects of budesonide colonic localization tablet by comparing the budesonide concentration in gastrointestinal tissue after oral administration of different budesonide preparations.结论布地奈德结肠定位片具有显著的结肠靶向性。
6)oral colon-specific口服结肠靶向
1.Starch can not be digested in the upper gastrointestinal but can be microbially decomposed in colon by suitable modifications which control starch digestibility, thus it can be used as carrier fororal colon-specific drug delivery system.通过合理改性来调控淀粉的消化性能,使其具有不被上消化道消化、但能够被结肠微生物酵解的特性,则可用作口服结肠靶向药物控释载体。
延伸阅读
靶向给药分子式：CAS号：性质：靶制剂选择性地与靶细胞结合产生药理效应的过程。由于不同的给药途径药靶物制剂可以进入不同的位置，而产后不同的靶向性和作用特点。如脂质体制剂，可以静脉、腹腔、肌肉、皮下或淋巴结注射，也可以支气管给药或大脑内、脊椎给药。静脉给药时，脂质体在体内优先被富含网状内皮细胞的组织（肝脾）所摄取，并迅速被单核吞噬细胞吞噬和降解。主要包括脂质体给药系统、受体靶向及磁性药物。脂质体制剂是把药物包裹在双分子脂质膜中，此种磷脂膜与生物膜类似，成为药物的载体，它与细胞膜亲和力强，使癌细胞摄取增多，提高疗效，增加耐受性。受体靶向是利用脂质体的表面有共价键与抗肿瘤细胞表面抗原的单克隆抗体结合，使脂质体在肿瘤细胞内大量集中，提高抗肿瘤细胞的选择性。磁性药物是指药物与高磁性的硫酸铁结合，在给药后，体外使用强大的磁场，使肿瘤部位处于此种强大磁场之下，药物被选择性地集中在肿瘤细胞，提高治疗指数。
