脑靶向,brain targeting
1)brain targeting脑靶向
1.OBJECTIVE To study the thebrain targeting effect of Evans blue chitosan microspheres and its nasal toxity.方法:采用交联固化法制备伊文思蓝壳聚糖微球;大鼠鼻腔给药,以脑部伊文思蓝含量为指标考察伊文思蓝壳聚糖微球的脑靶向性;以蛙上腭纤毛持续摆动时间为指标考察伊文思蓝壳聚糖微球对鼻腔纤毛的毒性;取鼻腔黏膜做组织切片,考察黏膜的病理变化。
英文短句/例句
1.Prepare and Appraise the Brain-targeted Liposome P-MMA-DOSPER;制备和鉴定脑靶向性脂质体P-MMA-DOSPER
2.Gene delivery targeted to the brain using an Angiopep-conjugated polyethyleneglycol-modified polyamidoamine dendrimerAngiopep修饰的脑靶向基因药物递释系统
3.Synthesis and Characterization of the Potential Prodrugs for the CNS Delivery of Tacrine;脑靶向他克林前体药物的合成及性质的研究
4.Study on Brain Targeting Delivery Systems of Antineoplastic Drug Raltitrexed;抗肿瘤药雷替曲塞的脑靶向给药系统研究
5.Research of Superoxide Dismutase and Catalase Enzyme Brain Targeting Drug Delivery System for Alzheimer s Disease;治疗老年痴呆症脑靶向复酶给药系统的研究
6.Study on Intranasal Brain-Targeting System of Trybizine Hydrochloride;盐酸锥双净经鼻脑靶向给药系统的研究
7.Studies on Brain-targeting Dendrimer-based Nano-scaled Gene Delivery System;脑靶向树枝状高分子纳米基因递释系统的研究
8.Study the Brain-targeting Nanoparticles of HDAPC, an Analog of EM-1内吗啡肽-1类似物HDAPC的脑靶向纳米粒研究
9.Preliminary evaluation of brain targeting via intranasal administration of galanthamine hydrobromide氢溴酸加兰他敏经鼻脑靶向性初步评价
10.AimTo study the therapeutic efficiency of amphotericin B liposome( AmB-L) targeting to the brain in mice with meningitis.目的研究两性霉素B脑靶向脂质体对小鼠脑膜炎的治疗作用。
11.Studies on Intranasal Brain Drug Targeting Delivery System for Galanthamine Hydrobromide氢溴酸加兰他敏鼻腔给药脑靶向传递系统的研究
12.Preliminary Study on Brain-targeted Delivery of Human Interferon α2b following Intratympanic Administration干扰素经鼓室给药靶向脑的初步研究
13.Experimental Study on Synergistic Targeting Restraint Effect of ATRA/BCNU Against Human Brain Tumor Stem Cells;ATRA协同BCNU靶向抑制人脑肿瘤干细胞的实验研究
14.Studies on Preparation of Ginkgolide-polybutylcyanoacrylate Nanoparticles and Brain Targeting Effect of Mice;银杏内酯纳米粒制备与小鼠脑部靶向作用研究
15.Targeted Opening of Blood-Brain Barrier Using MRI-Guided Focused Ultrasound Associated with Microbubbles;MRI引导聚焦超声联合微泡靶向开放血脑屏障
16.Treatment of Schizophrenia with Intracerebral Multi-Targets Stereotactic Lesions立体定向脑内多靶点联合毁损治疗精神分裂症
17.MRI-guided targeted blood-brain barrier disruption and drug delivery to rabbit brain with focused ultrasoundMRI引导与监测聚焦超声靶向开放血脑屏障兔脑给药
18.Bone Marrow-derived Mesenchymal Stem Cells in the Treatment of Glioblastomas;骨髓来源的间充质干细胞靶向治疗脑胶质瘤的实验研究
相关短句/例句
brain-targeting脑靶向
1.Thebrain-targeting effect of the prepared preparation was investigated using 1 injection and 1 liposomes as the control groups.以1粉针剂和1脂质体为对照,评价纳米粒的脑靶向作用。
2.Aimed at short half life and strong side-effect of antidepressant Venlafaxine, we have changed its structure, synthesized its prodrugs and evaluatedbrain-targeting effect of its prodrugs.脑靶向治疗药物具有治疗特异性强和副作用小的优点，是此病防治药物研究的重要发展方向。
3)brain-targeted drug delivery脑靶向给药
1.Preliminary study onbrain-targeted drug delivery via inner ear;本文探寻经内耳途径输送药物到脑部的可行性,为脑靶向给药提供一条崭新的研究思路。
4)brain targeting via intranasal administration经鼻脑靶向
1.Preliminary evaluation ofbrain targeting via intranasal administration of galanthamine hydrobromide氢溴酸加兰他敏经鼻脑靶向性初步评价
5)brain targeting drug delivery system脑靶向给药系统
6)liposome targeting to the brain脑靶向脂质体
1.MethodsAmphotericin Bliposome targeting to the brain were prepared by film-sonication method.目的研究两性霉素B脑靶向脂质体对小鼠脑膜炎的治疗作用。
延伸阅读
靶向给药分子式：CAS号：性质：靶制剂选择性地与靶细胞结合产生药理效应的过程。由于不同的给药途径药靶物制剂可以进入不同的位置，而产后不同的靶向性和作用特点。如脂质体制剂，可以静脉、腹腔、肌肉、皮下或淋巴结注射，也可以支气管给药或大脑内、脊椎给药。静脉给药时，脂质体在体内优先被富含网状内皮细胞的组织（肝脾）所摄取，并迅速被单核吞噬细胞吞噬和降解。主要包括脂质体给药系统、受体靶向及磁性药物。脂质体制剂是把药物包裹在双分子脂质膜中，此种磷脂膜与生物膜类似，成为药物的载体，它与细胞膜亲和力强，使癌细胞摄取增多，提高疗效，增加耐受性。受体靶向是利用脂质体的表面有共价键与抗肿瘤细胞表面抗原的单克隆抗体结合，使脂质体在肿瘤细胞内大量集中，提高抗肿瘤细胞的选择性。磁性药物是指药物与高磁性的硫酸铁结合，在给药后，体外使用强大的磁场，使肿瘤部位处于此种强大磁场之下，药物被选择性地集中在肿瘤细胞，提高治疗指数。
